IHT Rendezvous: In Singapore's Immigration Debate, Sign of Asia's Slipping Middle Class?

BEIJING — Immigration is a hot-button issue nearly everywhere in the world, though the contours of the debate vary from place to place. In the United States, sweeping changes to the law may offer legal residency for millions of people who have entered the country illegally, my colleague Ashley Parker reports.

Here in Asia, in the nation of Singapore, the debate looks somewhat different: The government plans to increase the population from just over five million to a possible high of nearly seven million by 2030, via regulated, legal immigration. It’s provoking opposition.

So much so that on Saturday, about 3,000 people turned out for what some commentators said was one of the biggest demonstrations in the nation’s history. (If the number seems small, it reflects the tight political control exerted over Singapore life by the People’s Action Party, which has run the country for about half a century and discourages public protest.)

What are the contours of the debate in Singapore?

Concern over booming immigration, often focused on new arrivals from increasingly rich China, has been simmering in the nation, with many feeling that the immigrants don’t play by the same rules, that their manners are poor and that they are pushing up prices. That feeling crystallized last year when a wealthy Chinese man driving a Ferrari at high speed killed three people (including himself) in a nighttime accident.

(Similar sentiments are found in Hong Kong, as my colleagues Bettina Wassener and Gerry Mullany wrote.)

Vividly illustrating the resentment, Singaporeans sometimes call the wealthy immigrants “rich Chinese locusts,” according to an article in the Economic Observer’s Worldcrunch.

Less controversially, the article quoted Peng Hui, a professor of sociology at National Singapore University, as saying: “Singaporeans do not discriminate against the Chinese. On the contrary, they very much identify with their Chinese ancestry.” (Of course, rich Chinese are not the only new immigrants, but they are a major group, many commentators have pointed out.) “What the local people do not appreciate is the fact that Chinese people talk loudly in public, eat on the subway and like to squeeze through in a crowd or grab things,” Mr. Peng was quoted as saying.

So the Singapore government’s Population White Paper that passed in Parliament earlier this month, just before Chinese New Year, was bound to stir things up.

The government is presenting the rise in immigration as a target that is needed if Singapore, where immigrants already make up about 40 percent of the population, and which has the highest concentration of millionaires in the world, is to continue to flourish, reports said. Singaporeans just aren’t having enough children, said the prime minister, Lee Hsien Loong.

“In my view, in 2030, I think 6 million will not be enough to meet Singaporeans’ needs as our population ages because of this problem of the baby boomers and bulge of aging people,” Mr. Lee said in Parliament, adding that 6.9 million was not a target but a number to be used to help plan for infrastructure.

“Do we really need to increase our population by that much?” wrote a person called Chang Wei Meng in a letter to The Straits Times, according to Reuters. “What happened to achieving the Swiss standard of living?”

Gilbert Goh, a main organizer of the rally Saturday at Singapore’s Speaker’s Corner in a public park, said the protesters had a message: “They want to tell the government, please reconsider this policy. The turnout is a testimony that this policy is flawed and unpopular on the ground,” The Associated Press quoted Mr. Goh as saying.

Yet amid the familiar rhetoric about immigrants, heard around the world – they don’t fit in, they’re rude, they’re different – might something more important be going on here?

In a blog post on Singapore News Alternative, Nicole Seah, a politician who has run for Parliament and comments on social issues, wrote: “Along with many other Singaporeans, I oppose the White Paper.”

Why? She is looking for “a society that lives in harmony, rather than tense and overcrowded conditions,” she writes.

“Not the Singapore Inc. that has been aggressively forced down our throats the past few years – a Singapore which is in danger of becoming a transient state where people from all over, come, make their fortunes, and leave.”

Not “a Singapore that has become a playground for the rich and the people who can afford it. A Singapore where the middle class is increasingly drowned out because they do not have the social clout or sufficient representatives in Parliament to voice their concerns.”

Ms. Seah’s statements raise an interesting question: Is this part of a phenomenon that the columnist Chrystia Freeland has written about so ably for this newspaper, the ascendancy of a wealthy, “plutocrat” class and the slipping status of the middle class?

As Ms. Freeland wrote last week: “The most important fact about the United States in this century is that middle-class incomes are stagnating. The financial crisis has revealed an equally stark structural problem in much of Europe.” Is it hitting Asia, too, and does Singapore’s protest speak, at least in part, to this? Hong Kong’s dissatisfaction too?

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Beyoncé's Life Is But a Dream: The Best Moments















02/16/2013 at 11:05 PM EST



I am ... still singing!

Beyoncé's HBO documentary, Life Is But a Dream, aired Saturday night and it was a 90-minute whirlwind of music, dance and emotion. And though the singer, 31, has been everywhere recently (the Inauguration, the Super Bowl halftime show, Oprah's Next Chapter), the film was full of new and exciting moments. Here are my favorites:

Baby Bey: A home movie of Beyoncé as a little girl playing with bees made my jaw drop. The scene seems to prove what her fans believe: that she was born to be a superstar known as Queen B. I also loved seeing her singing – and being a typical, giggling teenager – with her sister Solange and Kelly Rowland.

The Heartbreak: From her frank discussion of firing her father as a manager to hearing "the saddest song" she's ever written after having miscarriage, the film – which Beyoncé produced and directed herself – had raw, emotional moments.

Mrs. Carter: Life is like a dream for Beyoncé and husband Jay-Z, who surprisingly shared intimate moments together – giddy over her pregnancy, singing Coldplay's "Yellow" to each other, enjoying solitude on a boat in an undisclosed, exotic location. You could feel the love when she toasted him on his birthday.

Blue Ivy: How cute is she?! When Beyoncé and Jay's baby girl, who turned 1 in January, appeared on the screen at the premiere of Life Is But a Dream at New York's Ziegfeld Theater, the crowd gasped and then let out a collective "aww." And I jammed my fingers on the TV screen the first time I watched, trying to pinch those cheeks. Seeing Beyoncé at home with a baby on her hip was a powerful reminder that the fierce superstar is human afterall.

The Music: Of course! Seeing her sing "Listen" with a gorgeously altered ending in a car convinced me of one thing: Beyoncé is definitely not human! I also loved seeing everything that went into her epic Billboard Music Awards performance of "Run the World (Girls)." I just wish I could do that dance. And is it me or does "Resentment" get grittier and angrier every time she performs it?

Praise Beysus and long live the Queen B!

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Hollywood directs its star power toward a campaign closer to home









A stylish crowd waited beneath a flashing marquee outside the Fonda Theatre. "Appearing tonight!" the sign read. "Eric Garcetti 4 Mayor."


In a city where political campaigns are typically waged at neighborhood meetings, not Hollywood concert halls, last week's star-studded fundraiser for Garcetti highlighted the entertainment industry's outsized role in this year's mayoral race. Talk show host Jimmy Kimmel started the show with a stand-up routine and musician Moby got the crowd of several hundred dancing. Actress Amy Smart urged everyone to tweet about the campaign, and actor Will Ferrell beamed in via video to pledge that if Garcetti is elected, every resident in the city will receive free waffles.


Hollywood is taking to City Hall politics like never before, veterans say, with power players such as Steven Spielberg leading a major fundraising effort and celebrities such as Salma Hayek weighing in via YouTube. A Times analysis of city Ethics Commission records found that actors, producers, directors and others in the industry have donated more than $746,000 directly to candidates, with some $462,000 going to Garcetti and $226,000 to City Controller Wendy Greuel.





Several of Greuel's big-name celebrity supporters, including Tobey Maguire, Kate Hudson and Zooey Deschanel, recently hosted a fundraiser for her at an exclusive club on the Sunset Strip. She is getting extra help from Spielberg and his former partners at DreamWorks, Jeffrey Katzenberg and David Geffen, who have given at least $150,000 and are raising more for an independent group funding a TV ad blitz on her behalf.


The burst of support is coming from an industry often maligned for paying little attention to local politics.


While Mayor Antonio Villaraigosa is often photographed at red carpet events and former Mayor Tom Bradley was famously close to actor Gregory Peck, serious Hollywood money and star power has tended to remain tantalizingly out of reach for local politicians. "It's no secret that the entertainment industry has never really focused on the city that houses it," said Steve Soboroff, who ran for mayor and lost in 2001.


Political consultant Garry South, who has worked on mayoral and gubernatorial campaigns, recalled having to pay celebrities to appear at fundraisers in the past. Hollywood has long embraced candidates in presidential and congressional elections, South said, in part because they have more influence over causes favored by celebrities.


"The mayor of L.A. is not going to get us out of Afghanistan. The mayor of L.A. is not going to determine whether or not gay marriage is legal," South said. "The local issues are just not as sexy."


But this year, if you're a part of the Hollywood establishment, chances are you've gotten invitations to fundraisers for Greuel, Garcetti or both.


The difference this time is that both candidates have worked to cultivate deep Hollywood connections, observers say. Garcetti has represented Hollywood for 12 years, overseeing a development boom and presiding over ceremonies to add stars — Kimmel recently got one — on the Hollywood Walk of Fame. Greuel is a former executive at DreamWorks, where she worked with the moguls who founded the studio. She has also served for 10 years on the board of the California Film Commission.


City Councilwoman Jan Perry and entertainment attorney Kevin James have reaped far less financial support from the industry, records show, although each claims a share of celebrity endorsements. Dick Van Dyke sponsored a fundraiser for Perry and Oscar winner Dustin Lance Black has given to James.


Agent Feroz Taj, who attended Garcetti's Moby concert, said a flurry of activity around the race, involving friends and colleagues, piqued his interest. He said he's never been involved in a political campaign, but now when he receives invites to Greuel events, he says he is supporting Garcetti.


Industry insiders have been buzzing about a letter they say is being circulated by an advisor to Spielberg and Katzenberg, urging people to give $15,000 to an independent group supporting Greuel. The DreamWorks founders have made a difference for Greuel in previous elections. In 2002, financial support from the studio executives and their allies helped her squeak out a victory in one of the closest City Council races in history.


This time around, billionaire media mogul Haim Saban is getting involved, providing his Beverly Hills estate for a Greuel fundraiser featuring U.S. Sen. Barbara Boxer (D-Calif.). Greuel has also received contributions from Tom Hanks and actresses Mariska Hargitay and Eva Longoria, neither of whom have given to a local political campaign before, according to records.


Garcetti, on the other hand, has picked up contributions from former Disney Chief Executive Michael Eisner, as well as newcomers to local politics Jake Gyllenhaal and Hayek, who once traveled with Garcetti on a global warming awareness mission to the South Pole. The actress released a video endorsing Garcetti and thanking him for helping her find her wallet in the snow.


Campaign consultant Sean Clegg linked the industry's burgeoning interest in mayoral politics to President Obama's election, which he said had "a catalyzing effect on Hollywood." Indeed, many Greuel and Garcetti supporters were Obama backers. Hayek hosted a fundraiser for Obama and Longoria served as a co-chair of his reelection campaign.


Clegg is a consultant for Working Californians, an independent campaign committee that hopes to raise and spend at least $2 million supporting Greuel, with donations from Spielberg and others in Hollywood, as well as the union representing Department of Water and Power employees.


Generally, Clegg argued, Hollywood money is different than the special-interest funding campaigns collect. "Money is coming out of the entertainment industry more on belief and less on the transactional considerations," he said.


But Raphael Sonenshein, director of the Pat Brown Institute of Public Affairs at Cal State L.A., said Hollywood's new interest in local elections may be tied to growing concerns about film production being lured elsewhere by tax incentives.


Garcetti and Greuel have both pledged to reverse job losses tied to runaway television and film production, with Garcetti touting a recent proposal to eliminate roughly $231,000 in annual city fees charged for pilot episodes of new TV shows. The number of pilots shot locally has dropped 30% in recent years, but city budget analysts say the tax break would have a minimal effect because city fees represent only a small portion of production costs.


On the council, both candidates voted to eliminate filming fees at most city facilities. Greuel tells audiences she has an insider's perspective on the industry's needs and says she will create an "entertainment cabinet" to help it thrive. "I have sat with studio heads," she said in a recent interview. "They want a city . . . that is a champion for film industry jobs in Los Angeles."


Greuel may have Garcetti beat on experience in the studio front office, but he is the only candidate with his own page on IMDb.com — a closely watched industry website that tracks individuals' film and television credits.


The councilman, a member of the Screen Actors Guild, has made several television appearances, including one for the cable police drama "The Closer." He played the mayor of Los Angeles.


kate.linthicum@latimes.com


Times staff writer Maloy Moore contributed to this report.





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UN warns risk of hepatitis E in S. Sudan grows


GENEVA (AP) — The United Nations says an outbreak of hepatitis E has killed 111 refugees in camps in South Sudan since July, and has become endemic in the region.


U.N. refugee agency spokesman Adrian Edwards says the influx of people to the camps from neighboring Sudan is believed to be one of the factors in the rapid spread of the contagious, life-threatening inflammatory viral disease of the liver.


Edwards said Friday that the camps have been hit by 6,017 cases of hepatitis E, which is spread through contaminated food and water.


He says the largest number of cases and suspected cases is in the Yusuf Batil camp in Upper Nile state, which houses 37,229 refugees fleeing fighting between rebels and the Sudanese government.


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India Ink: Newswallah: Bharat Edition

Jammu and Kashmir: A week-long curfew in the Kashmir Valley that was imposed after the execution of the militant Muhammad Afzal was lifted Saturday, NDTV reported. Supporters of Mr. Afzal, who hailed from the Sopore town of Baramulla district, believed that he received an unfair trial for his role in the deadly Parliament attack case of 2001. Internet and television services have been restored in Kashmir after having been shut down, the report said.

Assam: At least 19 people died in violence during the civic polls in the state, India Today reported on Thursday. Chief Minister Tarun Gogoi admitted Wednesday to lapses by his government that led to the violence in some parts.  Thirteen people were killed when the security forces opened fire to control a mob that attacked polling officers in Goalpara district, the report noted.

Meghalaya: More than 100 of the 341 candidates who will be running in the upcoming state assembly polls own assets worth more than 10 million rupees, according to Meghalaya Election Watch, an independent organization, the Press Trust of India reported. The governing Congress party has fielded 35 such candidates and the two richest candidates are also from its ranks.

Gujarat: Prison officials at the Sabarmati Central Jail in Ahmedabad thwarted an attempted jailbreak last Sunday night, according to a Press Trust of India report on the NDTV Website. The attempted jailbreak comes as the trial of the 2008 Ahmedabad serial explosions is currently being conducted within the walls of the jail.  And 14 of the 68 accused in the case are lodged within the jail in a single barrack, where officials discovered that an 18-foot-long tunnel had been dug. The prison staff are suspected to have aided the jailbreak attempt, since work for the tunnel went undetected for 2 months, the report said.

Rajasthan: An MiF-27 aircraft of the Indian Air Force crashed in the Barmar district of Rajasthan on Tuesday, The Deccan Herald reported. While the plane crashed within minutes of takeoff from the Uttarlai base, there were no casualties and the pilot suffered only minor injuries.  A court of inquiry has been ordered to look into the crash, which was believed to have been caused by a technical defect.

Karnataka: The state got its new Lokayukta, or anti-corruption ombudsman, on Thursday, The Hindu reported. Y. Bhaskar Rao, the former chief justice of Karnataka State, filled the position that had been vacant for more than a year after his predecessor, Justice Shivraj V. Patil, was forced to resign following accusations of corruption in land deals.

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Molly Sims: I Nursed a Little Vampire!




Celebrity Baby Blog





02/15/2013 at 01:00 PM ET



Following the birth of her baby boy, Molly Sims was ready to sink her teeth into breastfeeding.


The only problem? Her son Brooks Alan had beaten her to it.


“Early on in the hospital, they really want you to breastfeed, so I’m trying everything,” the model mama, 39, shared during a Wednesday appearance on Anderson Live.


“And I’m like, ‘Gosh, this really, really hurts.’ And they’re like, ‘Oh, we know.’”


Determined to find the root of the pain, Sims went searching in her newborn’s mouth — and was shocked at her discovery.


“I’m like, ‘Is there any way a baby could be born with a tooth?’” she recalls. “And they went, ‘Oh sweetie, I know you’re a model, but … babies aren’t born with teeth!’”


She continues: “Come to find out, my baby was born with a tooth!”


Molly Sims Breastfeeding Anderson Live
Courtesy ANDERSON LIVE



Despite countless attempts to successfully nurse — “I did nipple shields, nipple guards, supplemental nursing system, it was horrible,” the new mom says — Sims eventually decided to call it quits.


“He was literally like a vampire on me for three months — it was unbelievable,” she says with a laugh. “Cut to I’m not breastfeeding and I’m proud of it.”


Now Brooks, 7 months, has moved on to other milestones — including crawling — and is already taking after his dad, Scott Stuber.


“He has the hairline of my husband. It’s like an Eddie Munster kind of hairline. It’s not so attractive, but [he'll] end up growing into it,” Sims says.


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UN warns risk of hepatitis E in S. Sudan grows


GENEVA (AP) — The United Nations says an outbreak of hepatitis E has killed 111 refugees in camps in South Sudan since July, and has become endemic in the region.


U.N. refugee agency spokesman Adrian Edwards says the influx of people to the camps from neighboring Sudan is believed to be one of the factors in the rapid spread of the contagious, life-threatening inflammatory viral disease of the liver.


Edwards said Friday that the camps have been hit by 6,017 cases of hepatitis E, which is spread through contaminated food and water.


He says the largest number of cases and suspected cases is in the Yusuf Batil camp in Upper Nile state, which houses 37,229 refugees fleeing fighting between rebels and the Sudanese government.


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India Ink: The 'One Billion Rising' on the Streets of Delhi

On Valentine’s Day in Delhi, the pink band was ubiquitous, tied around arms, on wrists and foreheads, around necks and backpacks. Printed on it were the words “Enough! No More Violence Against Women.”

On Thursday evening, as many set out for the customary Valentine’s Day dinner in the nation’s capital, several hundred men, women and children gathered at Parliament Street for an unorthodox celebration: a movement using music and dance to oppose violence against women.

“We don’t want violence; we want love,” said Kamla Bhasin, the movement’s South Asia coordinator, to a cheering crowd of about 500 people. She rejected love in the form of an Archies card or expensive jewelry, saying: “We want a just love, a love based on equality.”

In nearly 200 countries around the world, people took to the streets Thursday with a carnival spirit as part of One Billion Rising, a campaign initiated by Eve Ensler, the author of “The Vagina Monologues,” to highlight violence against women. In India, the message mirrored widespread public sentiment that has swelled after the gang rape and death of a 23-year-old physiotherapy student in Delhi in December, bringing women’s rights and safety to the center stage of civic and political discourse.

“This is a representation of our faith in the cause,” said Namrata Kumar, a 19-year-old student of philosophy, pointing to the dancing crowds at the event. “We can’t allow the government and ourselves to forget about this fight.”

The campaign Thursday was a continuation of that fight, but appeared to have taken on a different avatar. In recent months, young Indians have poured out in angry protests, condemning a police force that often exists for the preservation of power rather than the protection of people, and a political class that has routinely displayed apathy. For weeks, students, activists and others braved the Delhi winter, and the government’s lathis, or wooden staffs, and water cannons, to demand gender equality.

Thursday’s event, which was attended by dozens of young people from Delhi University and student organizations, seemed to herald a broader movement, one focused on changing societal mindsets and individual attitudes rather than railing against the government.

Ms. Bhasin chanted: “Women united!” The crowds roared back: “Will never be defeated!”

Many spoke of the recent events as a turning point that represented a new era of proactive fighting for gender justice.

“It’s very positive, very uplifting,” said Soumya Shankar, a 22-year-old political science student at Delhi University, as she swayed to the live performance of a popular traditional Indian song, “Lal Meri.” “This is not about a cause; it’s not about the angst. We are celebrating being women and being equal.”

To Ms. Shankar and many others, Thursday’s event was a testament to how some mindsets have already changed in a fairly short period of time. The evidence, she said, was that the crowd of young men and women had chosen to spend Feb.14 celebrating femininity rather than indulging in the “banal” proceedings that accompany an “overexposed Archies culture.”

The evening’s events, which lasted three hours, included a host of cultural performances: dances to the tunes of “Jai Ho,” an evocative song from “Slumdog Millionaire,” by men on wheelchairs and visually impaired women; a skit on domestic violence, which ended with a battered wife standing up to her abusive husband; recital of defiant poetry and inspirational songs by young women.

Standing alongside these women were scores of men, including Prateek Singh, a 28-year-old chef at a luxury hotel in Delhi, who had read about the event on Facebook. He had not been able to persuade his friends to join, he lamented. They were content, he said, with reading about horrific crimes against women and expressing relief that they had been spared similar attacks.

He had come out in part because he felt “suffocated,” he said, as he was viewed as a “threat” and a “sexual predator” because he is a man. He recounted a recent incident when he offered his seat on the Metro to a woman, but she eyed him with suspicion and declined.

On Thursday, Mr. Singh participated in a flash mob, choreographed by a group of young professionals to the beats of “Jago Delhi Jago,” a song they composed for the event. Hundreds clapped their hands and sprang up in the air, as they sang the words and cheered raucously.

Many had learned the dance routine in advance, having watched the instructional video online or attended the rehearsal last week in the city’s Deer Park. But many joined the mob spontaneously, mimicking those ahead of them.

“The idea is to get noticed, to be heard,” said Aseema Shukla, 18, a student at Delhi’s Indian Institute of Technology. “We don’t need to be heard in an angry or hurt voice, we can also be heard in a happy and cheerful way.”

Across the country, people mobilized to participate in One Billion Rising. Hundreds participated in the traditional dance of garba in Gujarat; In Bhopal, the actress and activist Shabani Azmi addressed a large crowd; In Mumbai, a star studded event saw dozens come out to dance and sing.

Celebrating this “changing social consciousness” was the television host Richa Anirudh, accompanied by her teenage daughter and 57-year-old mother at the Parliament Street event in Delhi. Ms. Anirudh recounted an incident when she was 21 and was harassed on a bus. At the time, she hoped that she would have enough money so that her daughter would never have to take the bus. Today, she said, she feels otherwise.

“The environment has to change; the people on the bus have to change, and it won’t happen if we run away from it,” said Ms. Anirudh, 38. “I want to participate in the change.”

Echoing this sentiment, Ms. Bhasin demanded freedom: “for walking freely, for talking freely, for dancing madly, for singing loudly.”

Crowds cheered, flags waved and the pink bands rose.

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Angelina Jolie Looks 'Totally Peaceful' in Hollywood















02/15/2013 at 06:00 AM EST



Angelina Jolie had lunch – sans Brad Pitt or their children – at Public at the Hollywood Roosevelt Hotel on Tuesday afternoon.

While the actress recently spoke about her "very grounded home," she "beamed" as she joined four women and one man at a corner booth near the bar for a mid-day meal.

The actress-turned-director looked "stunning in a long black fitted coat, a Louis Vuitton tote and her hair down," an onlooker tells PEOPLE. "She looked breathtaking with no makeup on."

As the group enjoyed a "carefree" lunch, Jolie was smiling and "seemed really comfortable and totally peaceful. Just having a nice lunch," the source adds.

– Jennifer Garcia


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Study: Fish in drug-tainted water suffer reaction


BOSTON (AP) — What happens to fish that swim in waters tainted by traces of drugs that people take? When it's an anti-anxiety drug, they become hyper, anti-social and aggressive, a study found. They even get the munchies.


It may sound funny, but it could threaten the fish population and upset the delicate dynamics of the marine environment, scientists say.


The findings, published online Thursday in the journal Science, add to the mounting evidence that minuscule amounts of medicines in rivers and streams can alter the biology and behavior of fish and other marine animals.


"I think people are starting to understand that pharmaceuticals are environmental contaminants," said Dana Kolpin, a researcher for the U.S. Geological Survey who is familiar with the study.


Calling their results alarming, the Swedish researchers who did the study suspect the little drugged fish could become easier targets for bigger fish because they are more likely to venture alone into unfamiliar places.


"We know that in a predator-prey relation, increased boldness and activity combined with decreased sociality ... means you're going to be somebody's lunch quite soon," said Gregory Moller, a toxicologist at the University of Idaho and Washington State University. "It removes the natural balance."


Researchers around the world have been taking a close look at the effects of pharmaceuticals in extremely low concentrations, measured in parts per billion. Such drugs have turned up in waterways in Europe, the U.S. and elsewhere over the past decade.


They come mostly from humans and farm animals; the drugs pass through their bodies in unmetabolized form. These drug traces are then piped to water treatment plants, which are not designed to remove them from the cleaned water that flows back into streams and rivers.


The Associated Press first reported in 2008 that the drinking water of at least 51 million Americans carries low concentrations of many common drugs. The findings were based on questionnaires sent to water utilities, which reported the presence of antibiotics, sedatives, sex hormones and other drugs.


The news reports led to congressional hearings and legislation, more water testing and more public disclosure. To this day, though, there are no mandatory U.S. limits on pharmaceuticals in waterways.


The research team at Sweden's Umea University used minute concentrations of 2 parts per billion of the anti-anxiety drug oxazepam, similar to concentrations found in real waters. The drug belongs to a widely used class of medicines known as benzodiazepines that includes Valium and Librium.


The team put young wild European perch into an aquarium, exposed them to these highly diluted drugs and then carefully measured feeding, schooling, movement and hiding behavior. They found that drug-exposed fish moved more, fed more aggressively, hid less and tended to school less than unexposed fish. On average, the drugged fish were more than twice as active as the others, researcher Micael Jonsson said. The effects were more pronounced at higher drug concentrations.


"Our first thought is, this is like a person diagnosed with ADHD," said Jonsson, referring to attention deficit-hyperactivity disorder. "They become asocial and more active than they should be."


Tomas Brodin, another member of the research team, called the drug's environmental impact a global problem. "We find these concentrations or close to them all over the world, and it's quite possible or even probable that these behavioral effects are taking place as we speak," he said Thursday in Boston at the annual meeting of the American Association for the Advancement of Science.


Most previous research on trace drugs and marine life has focused on biological changes, such as male fish that take on female characteristics. However, a 2009 study found that tiny concentrations of antidepressants made fathead minnows more vulnerable to predators.


It is not clear exactly how long-term drug exposure, beyond the seven days in this study, would affect real fish in real rivers and streams. The Swedish researchers argue that the drug-induced changes could jeopardize populations of this sport and commercial fish, which lives in both fresh and brackish water.


Water toxins specialist Anne McElroy of Stony Brook University in New York agreed: "These lower chronic exposures that may alter things like animals' mating behavior or its ability to catch food or its ability to avoid being eaten — over time, that could really affect a population."


Another possibility, the researchers said, is that more aggressive feeding by the perch on zooplankton could reduce the numbers of these tiny creatures. Since zooplankton feed on algae, a drop in their numbers could allow algae to grow unchecked. That, in turn, could choke other marine life.


The Swedish team said it is highly unlikely people would be harmed by eating such drug-exposed fish. Jonsson said a person would have to eat 4 tons of perch to consume the equivalent of a single pill.


Researchers said more work is needed to develop better ways of removing drugs from water at treatment plants. They also said unused drugs should be brought to take-back programs where they exist, instead of being flushed down the toilet. And they called on pharmaceutical companies to work on "greener" drugs that degrade more easily.


Sandoz, one of three companies approved to sell oxazepam in the U.S., "shares society's desire to protect the environment and takes steps to minimize the environmental impact of its products over their life cycle," spokeswoman Julie Masow said in an emailed statement. She provided no details.


___


Online:


Overview of the drug: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html


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